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Leave it to Lady Gaga to make her mark on the MTV Video Music Awards! This time the singing sensation opened the awards ceremony by performing You and I as her male alter-ego, Joe Calderone. She not only performed in a man's white T-shirt, black jeans and a Grease-style wig, she also presented the lifetime achievement award to Britney Spears known as the Michael Jackson Vangard Award.

Check out more from the MTV VMAs here.